Gotu Kola Extract Cosmetics Plant Extracts 80% Asiaticoside For Skin Care ，Barrier Repair & Anti-Irritation ，For Sensitive Or Acne-Prone Skin

Gotu Kola Extract

Latin Name Centella asiatica(L.)Urban

Family Umbelliferae
Part of the Plant Used Whole Herb

Product Introduction
Gotu Kola (Centella asiatica), a revered medicinal herb with millennia of therapeutic use across Traditional Chinese Medicine, Ayurveda, and Indonesian folk practices, is distinguished by its high concentration of bioactive triterpenoids. Key constituents include asiaticoside and madecassoside (triterpenoid glycosides), alongside their aglycone derivatives asiatic acid and madecassic acid (free triterpenoid acids).

Clinically validated for enhancing cutaneous wound repair, Gotu Kola extract demonstrates dual mechanisms:

1. Collagenesis stimulation via TGF-β/Smad pathway activation.

2. Anti-inflammatory action through NF-κB and COX-2 inhibition.

This evidence-based efficacy positions it as a gold-standard ingredient in dermatological formulations (e.g., post-procedure recovery creams, scar management serums) and cosmeceuticals targeting barrier restoration.

Active Ingredients

Triterpenes, Asiaticoside & Madecassoside

Product Specification

10%/ 20% / 40% / 70%/ 80% Total triterpenes(Asiaticoside & Madecassoside)

Physiological Functions

1. Skin Repair & Regeneration
   Demonstrates significant efficacy in accelerating the repair of damaged skin tissue, making it a key ingredient for topical dermatological treatments and advanced skincare formulations.

2. Cellular Activation & DNA Synthesis
   Stimulates the activity of HSKα (Human Skin Keratinocyte Activator) and HSFβ (Heat Shock Factor Beta), while enhancing DNA synthesis to support cellular regeneration and tissue renewal.

3. Wound Healing & Tissue Reconstruction
   Promotes rapid wound closure by accelerating granulation tissue formation and epithelialization, critical for post-traumatic and post-surgical recovery.

4. Antioxidant & Anti-Aging Properties
   Exhibits potent free radical scavenging capabilities, reducing oxidative stress to mitigate cellular aging and improve skin elasticity.

5. Neuroprotective Effects
   Shows clinically observed antidepressant activity through modulation of neurotransmitter pathways, supporting mental wellness applications.

Applications
 Pharmaceuticals: Incorporated into wound dressings, burn ointments, and post-procedure recovery gels for its regenerative properties.
 Nutraceuticals: Formulated into dietary supplements targeting oxidative stress reduction and cellular health enhancement.
 Dermocosmetics: Core component of anti-aging serums, barrier-repair creams, and medical-grade skincare lines.