Chlorogenic acid is one of the main antibacterial and antiviral effective pharmacological components of Eucommia ulmoides leaves. Hemihydrate is needle-like crystals (water). It becomes an anhydrous compound at 110 ° C, melting point: 208 ° C, [α] 20D-35.2. (C = 2.8). The solubility in water at 25 ° C is 4%, and the solubility in hot water is greater. Easily soluble in ethanol and acetone, very slightly soluble in ethyl acetate.
Chlorogenic acid has a broad antibacterial effect, but it can be inactivated by protein in the body. Similar to caffeic acid, oral or intraperitoneal injection can increase the central excitability of rats. It can increase the intestinal motility of rats and mice and the tension of rat uterus. It has a choleretic effect and can promote bile secretion in rats. It has a sensitizing effect on people. After inhalation of plant dust containing this product, asthma, dermatitis, etc. may occur.
1,Strong anti-inflammatory and anti-inflammatory effect,it has inhibitory effects on E. coli, Staphylococcus aureus, pneumococcus, gram negative and positive bacteria , and promote wound healing.The related Research Institute in Japan has confirmed that the alkaline substance extracted from Eucommia ulmoides has the function of resisting the human immune system virus, which has possible to used to prevent AIDS.
2, Obvious effects on anti free radical both in vivo and in vitro. It can effectively remove DPPH free radical, hydroxyl radical and superoxide anion radical, anti-oxidation of low density lipoprotein, protect tissue from oxidative damage and slow done bone senescence.
3, Chlorogenic acid has the effect of preventing cancer by reducing the utilization rate of carcinogens. And has effect on colorectal cancer, liver cancer and laryngeal cancer, and is considered to be an effective chemical protective agent for cancer.
4, Lowering blood pressure with stable effect, nontoxic and no side effects.The University of Wisconsin found that the effective lowering blood pressure components of Eucommia are Pinoresinol diglucoside, aucubin, chlorogenic acid, and eucommia chlorogenic acid 327-97-9polysaccharide.